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CS-5100

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The Sysmex CS-5100 system is a high throughput, best in class coagulation analyser with the added advantage of automated pre-analytical sample quality check to maximise the benefit of integrating coagulation testing into the LAS (laboratory automated transport system). This fulfils customers’ needs for both speed and quality.

CS-5100

High volume, fully automated, wagon-mounted haemostasis that is compatible with laboratory automated transport systems.

The CS-5100 system addresses the need of high-volume laboratories with its optimised throughput including full random access loading. It utilises Sysmex proprietary multi-wavelength analysis technology to deliver the high-quality results and provide extra safety to patient results via pre-analytical sample check. The advanced technology consolidates both routine and speciality haemostasis testing in a single analyser.

Exceptional productivity and efficiency

  • Using a multi-wavelength detection system, the CS-5100 system simultaneously measures multiple parameters using four different measurement methods: clotting, chromogenic, immunoassay and aggregation, all on a single platform, with a maximum throughput of 400 tests per hour.
  • With the option to connect CS-5100 system to a LAS, laboratories can achieve greater efficiency. LAS connectivity permits direct sampling, without the need for robotic arms, yielding greater reliability. Sampling can be interrupted through the STAT/Sampler unit for urgent sampling for greater efficiency.

High quality results and extra safety

  • Optimal wavelength is used for each measurement parameter to reduce effects of interfering substances on the absorbance spectra or in specific sample conditions such as low fibrinogen level or severe lipaemia.
  • Sample integrity such as the presence of interfering substances in the sample – haemolysis, icterus, lipaemia (HIL) and primary tube sample volume is checked before analysis. Results are flagged if the sample is of questionable quality for extra safety.

This onboard pre-analytical check further streamlines the sample handling process on LAS.

New standard in haemostasis testing

  • The CS-5100 system set a new standard in haemostasis testing, focusing strongly on clinical value and diagnostic benefits for both laboratories and clinicians. It automates speciality testing such as FXIII activity, platelet-based von Willebrand cofactor activity, platelet aggregation to ADP, epinephrine, collagen, arachidonic acid and ristocetin in a single analyser.
  • The 1st and 2nd derivatives are available from the clot waveform analysis for research in potential clinical utility of evaluating coagulation function in various bleeding disorders, especially Haemophilia A, B, and monitoring bypass therapy1.

1. Shima M, Thachil J, Nair SC, Srivastava A.Towards standardization of clot waveform analysis and recommendations for its clinical applications. J Thromb Hemost. 2013; 11:1417-20

  • PT: Dade Innovin, Thromborel S
  • APTT: Dade Actin, Dade Actin FS, Dade Actin FSL, Pathromtin SL
  • Fibrinogen: Dade Thrombin, Dade Fibrinogen Determination Reagent
  • Thrombin Time: Test Thrombin, Thromboclotin
  • Batroxobin Time: Batroxobin
  • Factor Deficiency: Factor II, V, VII, VIII, IX, X, XI, XII
  • Lupus Anticoagulant: LA1 Screen, LA2 Confirmation
  • Protein C Pathway: ProC Global, Protein C Reagent, Berichrom Protein C, Protein S Ac, Innovance Free Protein S Antigen
  • Antithrombin: Innovance Antithrombin, Berichrom Antithrombin III (A)
  • D-Dimer: Innovance D-Dimer
  • Von Willebrand Factor: vWF Ag, Innovance vWF Ac, BC von Willebrand
  • Chromogenic: Factor VIII Chromogenic, Berichrom Factor XIII Chromogenic, Berichrom C-1 Inhibitor, Berichrom α2-Antiplasmin, Berichrom Plasminogen
  • Heparin: Biophen Heparin LRT
  • Direct Thrombin Inhibitors: Hemoclot Thrombin Inhibitors, BIOPHEN DTI
  • Direct Factor Xa Inhibitors: Biophen Heparin LRT, Biophen DiXal
  • Platelet Aggregation: Revohem ADP, Revohem Collagen, Revohem Epinephrine, Revohem Arachidonic Acid, Revohem Ristocetin
Detection principles Multi-wavelength detector for transmitted light at 340, 405, 575, 660 and 800 nm
Detection channel/method 20 channels for clotting, chromogenic and immunoassays (8 of these channels are also be used for platelet aggregation assays)
Parameters up to 60 parameters can be analysed simultaneously
Throughput PT: 400 tests/h
PT/APTT: 400 tests/h
Sampling Continuous loading of maximum 10 racks of 10 tubes each, cap-piercing functionality
5 dedicated STAT positionsDirect sampling via left side of the analyser when connected to an optional Sysmex haemostasis island transportation system or other laboratory automation track system
Reagent holder 40 tilted reagent vial positions (10°C), 10 with mixing function
5 positions (room temperature)
All positions with positive reagent identification
Reference curves Maximum 10 reference curves per lot
Maximum 10 lots per parameter
Maximum 250 parameters
Quality control X-bar control, Levy-Jennings control
Multi-rule (Westgard Rule) monitoring
750 files with maximum 1,200 data points each
Data storage Up to 10,000 sample results with reaction curves
Printer Graphic or Data Printer (optional)
Dimensions (WxHxD)/weights Main unit:
1,030 × 1,280  × 1,150 mm, 278 kg (approximate)Pneumatic unit:
280 × 400 × 355 mm, 17 kg (approximate)
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CS-5100 brochure

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Features & Benefits

The CS-5100 system addresses the need of high-volume laboratories with its optimised throughput including full random access loading. It utilises Sysmex proprietary multi-wavelength analysis technology to deliver the high-quality results and provide extra safety to patient results via pre-analytical sample check. The advanced technology consolidates both routine and speciality haemostasis testing in a single analyser.

Exceptional productivity and efficiency

  • Using a multi-wavelength detection system, the CS-5100 system simultaneously measures multiple parameters using four different measurement methods: clotting, chromogenic, immunoassay and aggregation, all on a single platform, with a maximum throughput of 400 tests per hour.
  • With the option to connect CS-5100 system to a LAS, laboratories can achieve greater efficiency. LAS connectivity permits direct sampling, without the need for robotic arms, yielding greater reliability. Sampling can be interrupted through the STAT/Sampler unit for urgent sampling for greater efficiency.

High quality results and extra safety

  • Optimal wavelength is used for each measurement parameter to reduce effects of interfering substances on the absorbance spectra or in specific sample conditions such as low fibrinogen level or severe lipaemia.
  • Sample integrity such as the presence of interfering substances in the sample – haemolysis, icterus, lipaemia (HIL) and primary tube sample volume is checked before analysis. Results are flagged if the sample is of questionable quality for extra safety.

This onboard pre-analytical check further streamlines the sample handling process on LAS.

New standard in haemostasis testing

  • The CS-5100 system set a new standard in haemostasis testing, focusing strongly on clinical value and diagnostic benefits for both laboratories and clinicians. It automates speciality testing such as FXIII activity, platelet-based von Willebrand cofactor activity, platelet aggregation to ADP, epinephrine, collagen, arachidonic acid and ristocetin in a single analyser.
  • The 1st and 2nd derivatives are available from the clot waveform analysis for research in potential clinical utility of evaluating coagulation function in various bleeding disorders, especially Haemophilia A, B, and monitoring bypass therapy1.

1. Shima M, Thachil J, Nair SC, Srivastava A.Towards standardization of clot waveform analysis and recommendations for its clinical applications. J Thromb Hemost. 2013; 11:1417-20

Assay
  • PT: Dade Innovin, Thromborel S
  • APTT: Dade Actin, Dade Actin FS, Dade Actin FSL, Pathromtin SL
  • Fibrinogen: Dade Thrombin, Dade Fibrinogen Determination Reagent
  • Thrombin Time: Test Thrombin, Thromboclotin
  • Batroxobin Time: Batroxobin
  • Factor Deficiency: Factor II, V, VII, VIII, IX, X, XI, XII
  • Lupus Anticoagulant: LA1 Screen, LA2 Confirmation
  • Protein C Pathway: ProC Global, Protein C Reagent, Berichrom Protein C, Protein S Ac, Innovance Free Protein S Antigen
  • Antithrombin: Innovance Antithrombin, Berichrom Antithrombin III (A)
  • D-Dimer: Innovance D-Dimer
  • Von Willebrand Factor: vWF Ag, Innovance vWF Ac, BC von Willebrand
  • Chromogenic: Factor VIII Chromogenic, Berichrom Factor XIII Chromogenic, Berichrom C-1 Inhibitor, Berichrom α2-Antiplasmin, Berichrom Plasminogen
  • Heparin: Biophen Heparin LRT
  • Direct Thrombin Inhibitors: Hemoclot Thrombin Inhibitors, BIOPHEN DTI
  • Direct Factor Xa Inhibitors: Biophen Heparin LRT, Biophen DiXal
  • Platelet Aggregation: Revohem ADP, Revohem Collagen, Revohem Epinephrine, Revohem Arachidonic Acid, Revohem Ristocetin
Specifications
Detection principles Multi-wavelength detector for transmitted light at 340, 405, 575, 660 and 800 nm
Detection channel/method 20 channels for clotting, chromogenic and immunoassays (8 of these channels are also be used for platelet aggregation assays)
Parameters up to 60 parameters can be analysed simultaneously
Throughput PT: 400 tests/h
PT/APTT: 400 tests/h
Sampling Continuous loading of maximum 10 racks of 10 tubes each, cap-piercing functionality
5 dedicated STAT positionsDirect sampling via left side of the analyser when connected to an optional Sysmex haemostasis island transportation system or other laboratory automation track system
Reagent holder 40 tilted reagent vial positions (10°C), 10 with mixing function
5 positions (room temperature)
All positions with positive reagent identification
Reference curves Maximum 10 reference curves per lot
Maximum 10 lots per parameter
Maximum 250 parameters
Quality control X-bar control, Levy-Jennings control
Multi-rule (Westgard Rule) monitoring
750 files with maximum 1,200 data points each
Data storage Up to 10,000 sample results with reaction curves
Printer Graphic or Data Printer (optional)
Dimensions (WxHxD)/weights Main unit:
1,030 × 1,280  × 1,150 mm, 278 kg (approximate)Pneumatic unit:
280 × 400 × 355 mm, 17 kg (approximate)
Documents
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CS-5100 brochure

Download Here »